RESUMEN
The activity of azithromycin against enteritis-producing agents other than Campylobacter spp. was studied. The susceptibility to azithromycin, through gradient test, of 88 clinical isolates (51 Salmonella spp., 23 Aeromonas spp., 10 Shigella sonnei and 4 Yersinia enterocolitica) for one year was studied prospectively. The results were compared with the activity of ampicillin, trimethoprim-sulfamethoxazole and ciprofloxacin by microdilution. For azithromycin, the minimum inhibitory concentration (MIC) 50 and MIC90 were 4 and 12 mg/l, respectively. Six (6.8%) isolates were simultaneously resistant to ampicillin, trimethoprim- sulfamethoxazole and ciprofloxacin, and 3 (50%) of them presented a MIC >256 mg/l. Azithromycin may be a good empirical therapeutic option for the treatment of bacterial enteritis.
Asunto(s)
Aeromonas/efectos de los fármacos , Antibacterianos/farmacología , Azitromicina/farmacología , Enterobacteriaceae/efectos de los fármacos , Campylobacter , Gastroenteritis/microbiología , Humanos , Pruebas de Sensibilidad MicrobianaRESUMEN
No disponible
Asunto(s)
Humanos , Preescolar , Niño , Adolescente , Antígenos Bacterianos/aislamiento & purificación , Técnicas Bacteriológicas/métodos , Faringitis/microbiología , Streptococcus pyogenes/inmunología , Sensibilidad y Especificidad , Streptococcus pyogenes/aislamiento & purificación , Tonsilitis/microbiologíaRESUMEN
No disponible